Osteoporosis is a condition that causes bones to become brittle due to the loss of bone tissue. It originates from hormonal changes, calcium or vitamin D deficiencies, and aging. Osteoporosis can affect both men and women, however, women are more susceptible to it. Osteoporosis is why all of our grandmothers break their hips.
To understand osteoporosis, you must understand our bones. Many people don’t realize that the human skeleton is a complicated and dynamic organ. Bones are like skin or hair; they are living tissue that is constantly being absorbed and replaced. This process is called “Bone Remodeling.” Osteoporosis occurs when bone is lost at a faster rate than new bone is created. In severe cases, bones can break from activities as simple as bending over or coughing.
How does cannabis help our bones and treat osteoporosis?
As mentioned throughout our website, cannabinoid ligands are CB1, CB2 and TRPV1 receptor agonists that affect the human endocannabinoid system. Our internal endocannabinoid systems control many processes that are essential for life. The skeletal endocannabinoid system plays a critical role in regulating bone mass in health and in disease.
A 2010 experimental study concluded that cannabinoids may be an effective treatment for multifaceted bone diseases like osteoporosis. This was an in vivo study performed on mice. At a clinical level, humans and mice have a lot in common!
This study determined that endocannabinoids and their receptors are involved in the pathogenesis of osteoporosis. It found that pharmacological and genetic inactivation of the CB1, CB2, and GPR55 receptors in adult mice increase bone mass, suppress bone resorption, and protect against bone loss. This means that CB1 and CB2 agonists and antagonists may prevent or even reverse the pathology of osteoporosis and other bone diseases.
Perhaps the most exciting finding of this study is that cannabinoid ligands that affect the CB1, CB2, and GPR55 receptors can be administered orally without psychotropic effects. Translation: medical benefits with no smoking and no high.
Why aren’t U.S. doctors, scientists and universities studying this?
Because the DEA still classifies cannabis as a Schedule 1 narcotic. Schedule 1 narcotics are described as having a “high potential for abuse with no known medical uses.” This is the highest DEA schedule and includes drugs like heroin, PCP and crack. “Less dangerous” schedule 2 drugs include cocaine and opium. So according to the DEA, medical marijuana has no medicinal value and is more dangerous than cocaine, morphine and opium (continue reading after you stop laughing).
Marijuana’s schedule 1 status is more than just erroneous and obsolete, it stifles scientific and medical research. The DEA’s scheduling prevents scientists from legally researching the medical value of cannabis. It also prevents FDA studies and trials.
Pretty ridiculous, isn’t it? The DEA is preventing the best researchers in the world from studying a non-toxic and non-psychoactive drug that has the medical potential to improve all of our lives.
By: Daniel Macris, founder and ceo of Halcyon Organics.
© 2014 Halcyon Organics
Here are the two studies that were referenced in this article.
Originally published on Feb 13, 2014 @ 15:10